Introduction of Syringe Filter Membrane Material
Syringe filter units are used for small volume filtration of liquids, gas and other material-specified applications. They are available with many different membranes including Nylon, PTFE, Hydrophilic PTFE, PES, PVDF, MCE, CA, GF, PP, in both sterile and non-sterile varieties, and with or without pre-filters.Different membrane materials have different characteristics, described below.
* Nylon/Polyamide (NY)
Hydrophilic membrane. Resistant to a range of organic solvents. Suitable for use with high pH samples. Binds proteins, which makes it unsuitable for protein recovery applications.
Hydrophobic membrane. Resistant to organic solvents as well as strong acids and bases. Low protein binding. Low in extractables. Main applications are the filtration of non-aqueous samples. Prior to filtering of aqueous samples, the membrane must be pre-wetted with a water-miscible organic solvent.
* Hydrophilic Polytetrafluoroethylene (PTFE-L)
Hydrophilic PTFE membranes are unsupported membrane that ideal for HPLC and mixtures of aqueous and organic solvents. Use with both aqueous and organic solvents, along with their mixtures.
* Polyether Sulfone( PES )
Hydrophilic membrane. Broad solvent compatibility. Suitable for filtration of aqueous and compatible organic solvents. Higher liquid flow than either PTFE or PVDF. Low in extractables. Low protein binding.
* Cellulose Acetate (CA)
Hydrophilic membrane. Limited solvent resistance. Very low protein binding capacity, which makes it an excellent choice for protein recovery applications.
* Polyvinylidene Difluoride (PVDF)
Hydrophobic membrane. Fast flow rate and very low protein binding. Generally compatible with most common solvents. Ideal for protein recovery applications.
* Mixed Cellulose Esters(MCE)
Hydrophilic MCE membranes. A biologically inert mixture of Cellulose Acetate and Cellulose Nitrate membranes which have higher protein binding than CA for most proteins. High porosity provides high flow rate. Good use for aqueous based samples.
* Glass Microfiber/Glass Fiber (GMF/GF)
Hydrophilic material. Excellent compatibility with organic solvents and strong acids (apart from hydrofluoric acid) and bases. Either used as a prefilter or as a final filter.
* Polypropylene (PP)
Slightly hydrophobic membrane. Resistant to a wide range of organic solvents. Also good choice used as a prefilter or as a final filter.