C18-Alkaline HPLC Columns

Column: XChroma HPLC Column, C18-Alkaline, 4.6 ×250 mm, 5µm
Mobile Phase:
A: 0.5 mol/L KH2PO3(adjust pH to 3.5 with H3PO4): MeOH:water=10:30:60
B: 0.5 mol/L KH2PO3(adjust pH to 3.5 with H3PO4): MeOH:water=10:50:40
Flow Rate: 1.0 mL/min
Detector: 225nm
Temperature: 30℃
Injection Volume: 20μL



Starlab Scientific Co., Ltd C18-Alkaline with high purity silica gel is embedded in aqueous groups, making it aqueous. aqueous groups replace a large number of siloxyl sites, effectively preventing the interaction between alkaline substances and silicones.
Due to the embedding of aqueous groups, the selective and traditional anti-phase C18 and other chromatographic columns have obvious differences.


Unique bonding and end-capping technology
Optimization of chromatographic parameters such as surface area and carbon content
Excellent balances retention, separation, and pollution resistance
Average sample size & pore size make well flow rate
Perfect peak shape & high peak volume
Pure silica gel ensure high mechanical strength and high specific surface area
Spherical silica gel, good stability, improve separation efficiency and reproducibility
Ultra-dense bonding and double-ended ensure long life
Basic, acidic, and neutral compounds make excellent peak shape
Wide range of pH with long service life
Used with most HPLC instruments (Agilent, Biotage, Grace etc)


1. Embedded in the aqueous group
2. Aqueous groups replace a large number of siloxyl sites, which can make analysis of alkaline substances can obtain the perfect peak shape
3. High water phase ratio can be used to stabilize the flow
4. Quick separation of similar samples
5. pH Range: 1.5-10.0


1. Containing alkaloids ingredients Chinese medicine
2. Be separated by the mobile phase to quickly separate similar samples

C18-Alkaline HPLC Columns

Ordering Information

Item No Description Package (pcs/pk)
SLHC18AL546150 HPLC Column, C18-Alkaline, 5μm, 120Å, 4.6x150mm 1
SLHC18AL546250 HPLC Column, C18-Alkaline, 5μm, 120Å, 4.6x250mm 1

We have more than thirty lines for the production of micro-porous Membranes, Syringe filters, Sample vials, Septa and caps, along with Filter Paper, Vacuum pumps and manifolds.

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